Cargando…
Vav1 Down-Modulates Akt2 Expression in Cells from Pancreatic Ductal Adenocarcinoma: Nuclear Vav1 as a Potential Regulator of Akt Related Malignancy in Pancreatic Cancer
Pancreatic ductal adenocarcinoma (PDAC) is the most aggressive tumor malignancy worldwide, mainly due to uncontrolled metastasis. Among the numerous molecules deregulated in PDAC, different members of the Akt pathways are of great importance because they are involved in tumor cell proliferation, mig...
Autores principales: | Grassilli, Silvia, Brugnoli, Federica, Lattanzio, Rossano, Buglioni, Simonetta, Bertagnolo, Valeria |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600902/ https://www.ncbi.nlm.nih.gov/pubmed/32993067 http://dx.doi.org/10.3390/biomedicines8100379 |
Ejemplares similares
-
Vav1 downmodulates Akt in different breast cancer subtypes: a new promising chance to improve breast cancer outcome
por: Grassilli, Silvia, et al.
Publicado: (2018) -
Vav1 Selectively Down-Regulates Akt2 through miR-29b in Certain Breast Tumors with Triple Negative Phenotype
por: Grassilli, Silvia, et al.
Publicado: (2022) -
High nuclear level of Vav1 is a positive prognostic factor in early invasive breast tumors: a role in modulating genes related to the efficiency of metastatic process
por: Grassilli, Silvia, et al.
Publicado: (2014) -
Vav1 is necessary for PU.1 mediated upmodulation of miR‐29b in acute myeloid leukaemia‐derived cells
por: Vezzali, Federica, et al.
Publicado: (2018) -
Vav1 Sustains the In Vitro Differentiation of Normal and Tumor Precursors to Insulin Producing Cells Induced by all-Trans Retinoic Acid (ATRA)
por: Brugnoli, Federica, et al.
Publicado: (2020)