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Disruption of Cholinergic Circuits as an Area for Targeted Drug Treatment of Alzheimer’s Disease: In Vivo Assessment of Short-Term Plasticity in Rat Brain

The search for new therapeutics for the treatment of Alzheimer’s disease (AD) is still in progress. Aberrant pathways of synaptic transmission in basal forebrain cholinergic neural circuits are thought to be associated with the progression of AD. However, the effect of amyloid-beta (Aβ) on short-ter...

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Detalles Bibliográficos
Autores principales: Chavushyan, Vergine, Soghomonyan, Ani, Karapetyan, Gohar, Simonyan, Karen, Yenkoyan, Konstantin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600922/
https://www.ncbi.nlm.nih.gov/pubmed/33050228
http://dx.doi.org/10.3390/ph13100297