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Atg5-Deficient Mice Infected with Francisella tularensis LVS Demonstrate Increased Survival and Less Severe Pathology in Internal Organs

Francisella tularensis is a highly virulent intracellular pathogen that proliferates within various cell types and can infect a multitude of animal species. Francisella escapes the phagosome rapidly after infection and reaches the host cell cytosol where bacteria undergo extensive replication. Once...

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Detalles Bibliográficos
Autores principales: Kelava, Ina, Mihelčić, Mirna, Ožanič, Mateja, Marečić, Valentina, Knežević, Maša, Ćurlin, Marija, Štifter, Sanja, Sjöstedt, Anders, Šantić, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600933/
https://www.ncbi.nlm.nih.gov/pubmed/33036147
http://dx.doi.org/10.3390/microorganisms8101531