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Synthesis, Antiproliferative Activity, and DNA Binding Studies of Nucleoamino Acid-Containing Pt(II) Complexes

We here report our studies on the reaction with the platinum(II) ion of a nucleoamino acid constituted by the l-2,3-diaminopropanoic acid linked to the thymine nucleobase through a methylenecarbonyl linker. The obtained new platinum complexes, characterized by spectroscopic and mass spectrometric te...

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Detalles Bibliográficos
Autores principales: Riccardi, Claudia, Capasso, Domenica, Coppola, Angela, Platella, Chiara, Montesarchio, Daniela, Di Gaetano, Sonia, Roviello, Giovanni N., Musumeci, Domenica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600948/
https://www.ncbi.nlm.nih.gov/pubmed/33007911
http://dx.doi.org/10.3390/ph13100284