Evi1 Counteracts Anti-Leukemic and Stem Cell Inhibitory Effects of All-Trans Retinoic Acid on Flt3-ITD/Npm1c-Driven Acute Myeloid Leukemia Cells

All-trans retinoic acid (atRA) has a dramatic impact on the survival of patients with acute promyelocytic leukemia, but its therapeutic value in other types of acute myeloid leukemia (AML) has so far remained unclear. Given that AML is a stem cell-driven disease, recent studies have addressed the ef...

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Detalles Bibliográficos
Autores principales: Nguyen, Chi Huu, Grandits, Alexander M., Vassiliou, George S., Staber, Philipp B., Heller, Gerwin, Wieser, Rotraud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600968/
https://www.ncbi.nlm.nih.gov/pubmed/32998330
http://dx.doi.org/10.3390/biomedicines8100385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600968/
https://www.ncbi.nlm.nih.gov/pubmed/32998330
http://dx.doi.org/10.3390/biomedicines8100385

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