Production of ROS by Gallic Acid Activates KDM2A to Reduce rRNA Transcription

Metformin, which is suggested to have anti-cancer effects, activates KDM2A to reduce rRNA transcription and proliferation of cancer cells. Thus, the specific activation of KDM2A may be applicable to the treatment of cancers. In this study, we screened a food-additive compound library to identify com...

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Detalles Bibliográficos
Autores principales: Tanaka, Yuji, Obinata, Hideru, Konishi, Akimitsu, Yamagiwa, Noriyuki, Tsuneoka, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601038/
https://www.ncbi.nlm.nih.gov/pubmed/33050392
http://dx.doi.org/10.3390/cells9102266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601038/
https://www.ncbi.nlm.nih.gov/pubmed/33050392
http://dx.doi.org/10.3390/cells9102266

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