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Production of ROS by Gallic Acid Activates KDM2A to Reduce rRNA Transcription
Metformin, which is suggested to have anti-cancer effects, activates KDM2A to reduce rRNA transcription and proliferation of cancer cells. Thus, the specific activation of KDM2A may be applicable to the treatment of cancers. In this study, we screened a food-additive compound library to identify com...
Autores principales: | Tanaka, Yuji, Obinata, Hideru, Konishi, Akimitsu, Yamagiwa, Noriyuki, Tsuneoka, Makoto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601038/ https://www.ncbi.nlm.nih.gov/pubmed/33050392 http://dx.doi.org/10.3390/cells9102266 |
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