High Titer Persistent Neutralizing Antibodies Induced by TSST-1 Variant Vaccine Against Toxic Shock Cytokine Storm

Staphylococcal superantigen toxins lead to a devastating cytokine storm resulting in shock and multi-organ failure. We have previously assessed the safety and immunogenicity of a recombinant toxic shock syndrome toxin 1 variant vaccine (rTSST-1v) in clinical trials (NCT02971670 and NCT02340338). The...

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Detalles Bibliográficos
Autores principales: Roetzer, Andreas, Stich, Norbert, Model, Nina, Schwameis, Michael, Firbas, Christa, Jilma, Bernd, Eibl, Martha M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601046/
https://www.ncbi.nlm.nih.gov/pubmed/33023185
http://dx.doi.org/10.3390/toxins12100640

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601046/
https://www.ncbi.nlm.nih.gov/pubmed/33023185
http://dx.doi.org/10.3390/toxins12100640

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