Sphingolipid Pathway as a Source of Vulnerability in IDH1(mut) Glioma

SIMPLE SUMMARY: The presence of the IDH mutation in glioma raises the possibility that these CNS malignancies could be targeted with metabolic-based therapeutics, however, the exploration of the role that regulatory lipids, such as sphingolipids serve within the IDH1(mut) gliomas remains limited. Ou...

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Detalles Bibliográficos
Autores principales: Dowdy, Tyrone, Zhang, Lumin, Celiku, Orieta, Movva, Sriya, Lita, Adrian, Ruiz-Rodado, Victor, Gilbert, Mark R., Larion, Mioara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601159/
https://www.ncbi.nlm.nih.gov/pubmed/33050528
http://dx.doi.org/10.3390/cancers12102910

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601159/
https://www.ncbi.nlm.nih.gov/pubmed/33050528
http://dx.doi.org/10.3390/cancers12102910

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