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Blocking c-MET/ERBB1 Axis Prevents Brain Metastasis in ERBB2+ Breast Cancer

SIMPLE SUMMARY: Targeted monotherapies are ineffective in the treatment of brain metastasis of ERBB2(+) breast cancer (BC) underscoring the need for combination therapies. The lack of robust preclinical models has further hampered the assessment of treatment modalities. We report here a clinically r...

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Detalles Bibliográficos
Autores principales: Gautam, Shailendra K., Kanchan, Ranjana K., Siddiqui, Jawed A., Maurya, Shailendra K., Rauth, Sanchita, Perumal, Naveenkumar, Atri, Pranita, Venkata, Ramakanth C., Mallya, Kavita, Mirza, Sameer, Ponnusamy, Moorthy P., Band, Vimla, Mahapatra, Sidharth, Jain, Maneesh, Batra, Surinder K., Nasser, Mohd Wasim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601177/
https://www.ncbi.nlm.nih.gov/pubmed/33019652
http://dx.doi.org/10.3390/cancers12102838