Cargando…

Micromolar Valproic Acid Doses Preserve Survival and Induce Molecular Alterations in Neurodevelopmental Genes in Two Strains of Zebrafish Larvae

Autism spectrum disorders (ASDs) comprise a genetically heterogeneous group of conditions characterized by a multifaceted range of impairments and multifactorial etiology. Epidemiological studies have identified valproic acid (VPA), an anticonvulsant used to treat epilepsy, as an environmental facto...

Descripción completa

Detalles Bibliográficos
Autores principales: Messina, Andrea, Boiti, Alessandra, Sovrano, Valeria Anna, Sgadò, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601180/
https://www.ncbi.nlm.nih.gov/pubmed/32987891
http://dx.doi.org/10.3390/biom10101364