Assessment of CAR T Cell Frequencies in Axicabtagene Ciloleucel and Tisagenlecleucel Patients Using Duplex Quantitative PCR

SIMPLE SUMMARY: To monitor patients after CAR T cell treatment, measuring frequencies of chimeric antigen receptor (CAR) T cells is crucial. However, experimental assays to quantify CAR T cells are lacking. Here, we describe a quantitative single copy gene-based PCR approach to measure frequencies o...

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Detalles Bibliográficos
Autores principales: Schubert, Maria-Luisa, Kunz, Alexander, Schmitt, Anita, Neuber, Brigitte, Wang, Lei, Hückelhoven-Krauss, Angela, Langner, Sascha, Michels, Birgit, Wick, Antje, Daniel, Volker, Müller-Tidow, Carsten, Dreger, Peter, Schmitt, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601213/
https://www.ncbi.nlm.nih.gov/pubmed/33007926
http://dx.doi.org/10.3390/cancers12102820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601213/
https://www.ncbi.nlm.nih.gov/pubmed/33007926
http://dx.doi.org/10.3390/cancers12102820

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