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Inclusion Complex of Docetaxel with Sulfobutyl Ether β-Cyclodextrin: Preparation, In Vitro Cytotoxicity and In Vivo Safety

Docetaxel (DTX), as a first-line anti-tumor drug, has been studied for decades for its diverse bioactivities. However, DTX presents poor solubility in water, low bioavailability and serious toxic side effects which has hindered its application in the clinic. To address these problems, docetaxel-sulf...

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Detalles Bibliográficos
Autores principales: Ren, Lili, Yang, Xiaolong, Guo, Weilu, Wang, Jin, Chen, Guoguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601231/
https://www.ncbi.nlm.nih.gov/pubmed/33066097
http://dx.doi.org/10.3390/polym12102336