Epac1 Is Crucial for Maintenance of Endothelial Barrier Function through A Mechanism Partly Independent of Rac1

Epac1 (exchange protein activated by cAMP) stabilizes the endothelial barrier, but detailed studies are limited by the side effects of pharmacological Epac1 modulators and transient transfections. Here, we compare the key properties of barriers between endothelial cells derived from wild-type (WT) a...

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Detalles Bibliográficos
Autores principales: García-Ponce, Alexander, Schuster, Katharina, Døskeland, Stein-Ove, Reed, Rolf K., Curry, Fitz-Roy E., Waschke, Jens, Radeva, Mariya Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601253/
https://www.ncbi.nlm.nih.gov/pubmed/32992982
http://dx.doi.org/10.3390/cells9102170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601253/
https://www.ncbi.nlm.nih.gov/pubmed/32992982
http://dx.doi.org/10.3390/cells9102170

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