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Epac1 Is Crucial for Maintenance of Endothelial Barrier Function through A Mechanism Partly Independent of Rac1
Epac1 (exchange protein activated by cAMP) stabilizes the endothelial barrier, but detailed studies are limited by the side effects of pharmacological Epac1 modulators and transient transfections. Here, we compare the key properties of barriers between endothelial cells derived from wild-type (WT) a...
Autores principales: | García-Ponce, Alexander, Schuster, Katharina, Døskeland, Stein-Ove, Reed, Rolf K., Curry, Fitz-Roy E., Waschke, Jens, Radeva, Mariya Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601253/ https://www.ncbi.nlm.nih.gov/pubmed/32992982 http://dx.doi.org/10.3390/cells9102170 |
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