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Endoplasmic Reticulum Stress Affects Cholesterol Homeostasis by Inhibiting LXRα Expression in Hepatocytes and Macrophages

Atherosclerosis (AS) is the most common cardiovascular disease, and reverse cholesterol transport (RCT) plays an important role in maintaining cholesterol homeostasis. Both endoplasmic reticulum (ER) stress and LXRα can affect the metabolism of cholesterol. However, whether ER stress can modulate ch...

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Detalles Bibliográficos
Autores principales: Wang, Tian, Zhao, Yiyang, You, Zhongsheng, Li, Xiatian, Xiong, Mingdi, Li, Hua, Yan, Nianlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601278/
https://www.ncbi.nlm.nih.gov/pubmed/33050595
http://dx.doi.org/10.3390/nu12103088