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The Primary Cilium of Adipose Progenitors Is Necessary for Their Differentiation into Cancer-Associated Fibroblasts that Promote Migration of Breast Cancer Cells In Vitro

Cancer associated fibroblasts (CAFs) are central elements of the microenvironment that control tumor development. In breast cancer, CAFs can originate from adipose progenitors (APs). We, and others, have shown that the primary cilium, an antenna-shaped organelle, controls several aspects of APs’ bio...

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Detalles Bibliográficos
Autores principales: Peraldi, Pascal, Ladoux, Annie, Giorgetti-Peraldi, Sophie, Dani, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601294/
https://www.ncbi.nlm.nih.gov/pubmed/33049976
http://dx.doi.org/10.3390/cells9102251