Apoptosis, Induced by Human α-Synuclein in Yeast, Can Occur Independent of Functional Mitochondria

Human α-synuclein expression in baker’s yeast reportedly induces mitochondria-dependent apoptosis. Surprisingly, we find that, under de-repressing conditions of the inducible MET25/GAL1 promoters, yeast cells expressing chromosomally-integrated copies of the human α-synuclein gene are not killed, bu...

Descripción completa

Detalles Bibliográficos
Autores principales: Akintade, Damilare D., Chaudhuri, Bhabatosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601298/
https://www.ncbi.nlm.nih.gov/pubmed/33003464
http://dx.doi.org/10.3390/cells9102203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601298/
https://www.ncbi.nlm.nih.gov/pubmed/33003464
http://dx.doi.org/10.3390/cells9102203

Ejemplares similares