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Senescent Tumor CD8(+) T Cells: Mechanisms of Induction and Challenges to Immunotherapy
SIMPLE SUMMARY: Immunotherapies harness the hosts’ immune system to combat cancer and are currently used to treat many tumor types. Immunotherapies mainly target T cells, the major immune population responsible for tumor-cell killing. One of the reasons that T cells may not respond to immunotherapeu...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601312/ https://www.ncbi.nlm.nih.gov/pubmed/33008037 http://dx.doi.org/10.3390/cancers12102828 |