UCH-L1 inhibitor LDN-57444 hampers mouse oocyte maturation by regulating oxidative stress and mitochondrial function and reducing ERK1/2 expression

Oocyte maturation is a prerequisite for successful fertilization and embryo development. Incomplete oocyte maturation can result in infertility. Ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) has been found to be implicated in oocyte maturation and embryo development. However, the cellular and mol...

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Detalles Bibliográficos
Autores principales: Yuan, Pan, Zhou, Li, Zhang, Xiaona, Yao, Lan, Ning, Jun, Han, Xiao, Ming, Caifeng, Zhao, Yunhe, Zhang, Liqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Cell Death & Injury
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601359/
https://www.ncbi.nlm.nih.gov/pubmed/33030206
http://dx.doi.org/10.1042/BSR20201308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601359/
https://www.ncbi.nlm.nih.gov/pubmed/33030206
http://dx.doi.org/10.1042/BSR20201308

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