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A Multi-Omics Approach Identifies Key Regulatory Pathways Induced by Long-Term Zinc Supplementation in Human Primary Retinal Pigment Epithelium

In age-related macular degeneration (AMD), both systemic and local zinc levels decline. Elevation of zinc in clinical studies delayed the progression to end-stage AMD. However, the molecular pathways underpinning this beneficial effect are not yet identified. In this study, we used differentiated pr...

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Detalles Bibliográficos
Autores principales: Emri, Eszter, Kortvely, Elod, Dammeier, Sascha, Klose, Franziska, Simpson, David, den Hollander, Anneke I., Ueffing, Marius, Lengyel, Imre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601425/
https://www.ncbi.nlm.nih.gov/pubmed/33036197
http://dx.doi.org/10.3390/nu12103051