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Granzyme B Degraded Type IV Collagen Products in Serum Identify Melanoma Patients Responding to Immune Checkpoint Blockade

SIMPLE SUMMARY: Novel biomarkers that can identify melanoma patients responding to immune checkpoint inhibitor therapy are urgently needed. As high T-cell infiltration and low fibrotic activity are associated with response, we aimed to examine the serum biomarker potential of granzyme B degraded typ...

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Detalles Bibliográficos
Autores principales: Jensen, Christina, Sinkeviciute, Dovile, Madsen, Daniel Hargbøl, Önnerfjord, Patrik, Hansen, Morten, Schmidt, Henrik, Karsdal, Morten Asser, Svane, Inge Marie, Willumsen, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601429/
https://www.ncbi.nlm.nih.gov/pubmed/32998446
http://dx.doi.org/10.3390/cancers12102786