Efficacy of HDAC Inhibitors Belinostat and Panobinostat against Cisplatin-Sensitive and Cisplatin-Resistant Testicular Germ Cell Tumors

SIMPLE SUMMARY: There is a need for novel treatment options for patients with testicular germ cell tumors, especially for those that are resistant to standard chemotherapy, who show poor prognosis. In this work, we test two compounds that inhibit epigenetic enzymes called histone deacetylases—belino...

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Detalles Bibliográficos
Autores principales: Lobo, João, Guimarães-Teixeira, Catarina, Barros-Silva, Daniela, Miranda-Gonçalves, Vera, Camilo, Vânia, Guimarães, Rita, Cantante, Mariana, Braga, Isaac, Maurício, Joaquina, Oing, Christoph, Honecker, Friedemann, Nettersheim, Daniel, Looijenga, Leendert H. J., Henrique, Rui, Jerónimo, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601457/
https://www.ncbi.nlm.nih.gov/pubmed/33050470
http://dx.doi.org/10.3390/cancers12102903

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601457/
https://www.ncbi.nlm.nih.gov/pubmed/33050470
http://dx.doi.org/10.3390/cancers12102903

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