The NLRP3 inflammasome in macrophages is stimulated by cell‐free hemoglobin

Cell‐free hemoglobin (CFH) is associated with severe lung injury in human patients and is sufficient to induce airspace inflammation and alveolar–capillary barrier dysfunction in an experimental model of acute lung injury. The mechanisms through which this occurs are unknown. One key pathway which r...

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Detalles Bibliográficos
Autores principales: Shaver, Ciara M., Landstreet, Stuart R., Pugazenthi, Sangamithra, Scott, Fiona, Putz, Nathan, Ware, Lorraine B., Bastarache, Julie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Researchs
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601531/
https://www.ncbi.nlm.nih.gov/pubmed/33128438
http://dx.doi.org/10.14814/phy2.14589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601531/
https://www.ncbi.nlm.nih.gov/pubmed/33128438
http://dx.doi.org/10.14814/phy2.14589

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