Idebenone Protects against Spontaneous Chronic Murine Colitis by Alleviating Endoplasmic Reticulum Stress and Inflammatory Response

Endoplasmic reticulum (ER) stress in intestinal secretory goblet cells has been linked to the development of ulcerative colitis (UC). Emerging evidence suggests that the short chain quinone drug idebenone displays anti-inflammatory activity in addition to its potent antioxidant and mitochondrial ele...

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Detalles Bibliográficos
Autores principales: Shastri, Sonia, Shinde, Tanvi, Perera, Agampodi Promoda, Gueven, Nuri, Eri, Rajaraman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601570/
https://www.ncbi.nlm.nih.gov/pubmed/32998266
http://dx.doi.org/10.3390/biomedicines8100384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601570/
https://www.ncbi.nlm.nih.gov/pubmed/32998266
http://dx.doi.org/10.3390/biomedicines8100384

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