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Idebenone Protects against Spontaneous Chronic Murine Colitis by Alleviating Endoplasmic Reticulum Stress and Inflammatory Response
Endoplasmic reticulum (ER) stress in intestinal secretory goblet cells has been linked to the development of ulcerative colitis (UC). Emerging evidence suggests that the short chain quinone drug idebenone displays anti-inflammatory activity in addition to its potent antioxidant and mitochondrial ele...
Autores principales: | Shastri, Sonia, Shinde, Tanvi, Perera, Agampodi Promoda, Gueven, Nuri, Eri, Rajaraman |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601570/ https://www.ncbi.nlm.nih.gov/pubmed/32998266 http://dx.doi.org/10.3390/biomedicines8100384 |
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