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Cx43 and Associated Cell Signaling Pathways Regulate Tunneling Nanotubes in Breast Cancer Cells

SIMPLE SUMMARY: The gap junction protein connexin 43 (Cx43) facilitates direct intercellular communication and displays a complex dichotomous role in cancer. Here, we used breast cancer cell lines and CRISPR/Cas9 technology to dissect some of the poorly understood multimodal functions of Cx43 in thi...

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Detalles Bibliográficos
Autores principales: Tishchenko, Alexander, Azorín, Daniel D., Vidal-Brime, Laia, Muñoz, María José, Arenas, Pol Jiménez, Pearce, Christopher, Girao, Henrique, Ramón y Cajal, Santiago, Aasen, Trond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601615/
https://www.ncbi.nlm.nih.gov/pubmed/33003486
http://dx.doi.org/10.3390/cancers12102798