Synthesis of 4,4′-(4-Formyl-1H-pyrazole-1,3-diyl)dibenzoic Acid Derivatives as Narrow Spectrum Antibiotics for the Potential Treatment of Acinetobacter Baumannii Infections

Acinetobacter baumannii has emerged as one of the most lethal drug-resistant bacteria in recent years. We report the synthesis and antimicrobial studies of 25 new pyrazole-derived hydrazones. Some of these molecules are potent and specific inhibitors of A. baumannii strains with a minimum inhibitory...

Descripción completa

Detalles Bibliográficos
Autores principales: Delancey, Evan, Allison, Devin, KC, Hansa Raj, Gilmore, David F., Fite, Todd, Basnakian, Alexei G., Alam, Mohammad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601628/
https://www.ncbi.nlm.nih.gov/pubmed/32998384
http://dx.doi.org/10.3390/antibiotics9100650

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601628/
https://www.ncbi.nlm.nih.gov/pubmed/32998384
http://dx.doi.org/10.3390/antibiotics9100650

Ejemplares similares