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Differential Regulation of Telomeric Complex by BCR-ABL1 Kinase in Human Cellular Models of Chronic Myeloid Leukemia—From Single Cell Analysis to Next-Generation Sequencing

Telomeres are specialized nucleoprotein complexes, localized at the physical ends of chromosomes, that contribute to the maintenance of genome stability. One of the features of chronic myeloid leukemia (CML) cells is a reduction in telomere length which may result in increased genomic instability an...

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Detalles Bibliográficos
Autores principales: Deregowska, Anna, Pepek, Monika, Pruszczyk, Katarzyna, Machnicki, Marcin M., Wnuk, Maciej, Stoklosa, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601685/
https://www.ncbi.nlm.nih.gov/pubmed/33003326
http://dx.doi.org/10.3390/genes11101145