Age-Dependent Maturation of iPSC-CMs Leads to the Enhanced Compartmentation of β(2)AR-cAMP Signalling

The ability to differentiate induced-pluripotent stem cells into cardiomyocytes (iPSC-CMs) has opened up novel avenues for potential cardiac therapies. However, iPSC-CMs exhibit a range of somewhat immature functional properties. This study explored the development of the beta-adrenergic receptor (β...

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Detalles Bibliográficos
Autores principales: Hasan, Alveera, Mohammadi, Neda, Nawaz, Aisha, Kodagoda, Thusharika, Diakonov, Ivan, Harding, Sian E., Gorelik, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601768/
https://www.ncbi.nlm.nih.gov/pubmed/33053822
http://dx.doi.org/10.3390/cells9102275

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601768/
https://www.ncbi.nlm.nih.gov/pubmed/33053822
http://dx.doi.org/10.3390/cells9102275

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