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Overview of the Nucleic-Acid Binding Properties of the HIV-1 Nucleocapsid Protein in Its Different Maturation States

HIV-1 Gag polyprotein orchestrates the assembly of viral particles. Its C-terminus consists of the nucleocapsid (NC) domain that interacts with nucleic acids, and p1 and p6, two unstructured regions, p6 containing the motifs to bind ALIX, the cellular ESCRT factor TSG101 and the viral protein Vpr. T...

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Detalles Bibliográficos
Autores principales: Mouhand, Assia, Pasi, Marco, Catala, Marjorie, Zargarian, Loussiné, Belfetmi, Anissa, Barraud, Pierre, Mauffret, Olivier, Tisné, Carine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601788/
https://www.ncbi.nlm.nih.gov/pubmed/33003650
http://dx.doi.org/10.3390/v12101109