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Premature Vascular Aging with Features of Plaque Vulnerability in an Atheroprone Mouse Model of Hutchinson–Gilford Progeria Syndrome with Ldlr Deficiency

Hutchinson–Gilford progeria syndrome (HGPS) is among the most devastating of the laminopathies, rare genetic diseases caused by mutations in genes encoding nuclear lamina proteins. HGPS patients age prematurely and die in adolescence, typically of atherosclerosis-associated complications. The mechan...

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Detalles Bibliográficos
Autores principales: Nevado, Rosa M., Hamczyk, Magda R., Gonzalo, Pilar, Andrés-Manzano, María Jesús, Andrés, Vicente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601818/
https://www.ncbi.nlm.nih.gov/pubmed/33049978
http://dx.doi.org/10.3390/cells9102252