Targeting and Efficacy of Novel mAb806-Antibody-Drug Conjugates in Malignant Mesothelioma

Epidermal growth factor receptor (EGFR) is highly overexpressed in malignant mesothelioma (MM). MAb806 is a novel anti-EGFR antibody that selectively targets a tumor-selective epitope. MAb806-derived antibody drug conjugates (ADCs), ABT-414, ABBV-221 and ABBV-322, may represent a novel therapeutic s...

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Detalles Bibliográficos
Autores principales: Chia, Puey-Ling, Parakh, Sagun, Tsao, Ming-Sound, Pham, Nhu-An, Gan, Hui K., Cao, Diana, Burvenich, Ingrid J. G., Rigopoulos, Angela, Reilly, Edward B., John, Thomas, Scott, Andrew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601847/
https://www.ncbi.nlm.nih.gov/pubmed/33023139
http://dx.doi.org/10.3390/ph13100289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601847/
https://www.ncbi.nlm.nih.gov/pubmed/33023139
http://dx.doi.org/10.3390/ph13100289

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