Cargando…

Targeting and Efficacy of Novel mAb806-Antibody-Drug Conjugates in Malignant Mesothelioma

Epidermal growth factor receptor (EGFR) is highly overexpressed in malignant mesothelioma (MM). MAb806 is a novel anti-EGFR antibody that selectively targets a tumor-selective epitope. MAb806-derived antibody drug conjugates (ADCs), ABT-414, ABBV-221 and ABBV-322, may represent a novel therapeutic s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chia, Puey-Ling, Parakh, Sagun, Tsao, Ming-Sound, Pham, Nhu-An, Gan, Hui K., Cao, Diana, Burvenich, Ingrid J. G., Rigopoulos, Angela, Reilly, Edward B., John, Thomas, Scott, Andrew M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601847/ https://www.ncbi.nlm.nih.gov/pubmed/33023139 http://dx.doi.org/10.3390/ph13100289

Ejemplares similares

Tumor volumes as a predictor of response to the anti-EGFR antibody drug conjugate depatuxizumab mafadotin
por: Gan, Hui K, et al.
Publicado: (2021)

SEPPA-mAb: spatial epitope prediction of protein antigens for mAbs
por: Qiu, Tianyi, et al.
Publicado: (2023)

At R806
por: CERN PhotoLab
Publicado: (1976)

At R806
por: CERN PhotoLab
Publicado: (1976)

Antibody–Drug Conjugates for Cancer Therapy
por: Hafeez, Umbreen, et al.
Publicado: (2020)

Antibody Drug Conjugates in Glioblastoma – Is There a Future for Them?
por: Parakh, Sagun, et al.
Publicado: (2021)

Antibody-drug conjugates: beyond current approvals and potential future strategies
por: Menon, Siddharth, et al.
Publicado: (2022)

Protective mAbs and Cross-Reactive mAbs Raised by Immunization with Engineered Marburg Virus GPs
por: Fusco, Marnie L., et al.
Publicado: (2015)

DR5 mAb-conjugated, DTIC-loaded immuno-nanoparticles effectively and specifically kill malignant melanoma cells in vivo
por: Ding, Baoyue, et al.
Publicado: (2016)

The Different Colors of mAbs in Solution
por: Ambrogelly, Alexandre
Publicado: (2021)

Antibody–Drug Conjugates for Cancer Therapy
por: Parslow, Adam C., et al.
Publicado: (2016)

Correction: Protective mAbs and Cross-Reactive mAbs Raised by Immunization with Engineered Marburg Virus GPs
por: Fusco, Marnie L., et al.
Publicado: (2015)

Memorandum: R 806 extension
por: Willis, W J, et al.
Publicado: (1977)

Memorandum: R806 extension
por: Willis, W J
Publicado: (1979)

Memorandum: extension of R806
por: Rahm, David Charles
Publicado: (1978)

Memorandum: R 806 extension
por: Rahm, David Charles, et al.
Publicado: (1978)

Future plans for R806
por: CERN. Geneva. Intersecting Storage-Rings Committee
Publicado: (1976)

R806 (part 1)
por: CERN PhotoLab
Publicado: (1976)

Poster Sessions 602-806
Publicado: (2004)

Cellular tools for biosimilar mAb analysis
por: Lindemann, Carsten, et al.
Publicado: (2013)

Evolving trends in mAb production processes
por: Shukla, Abhinav A., et al.
Publicado: (2017)

State of the art in anti-cancer mAbs
por: Chiavenna, S. M., et al.
Publicado: (2017)

Memorandum: end of R806 running
por: Willis, W J
Publicado: (1977)

Status report of the R806T experiment
por: CERN. Geneva. Intersecting Storage-Rings Committee
Publicado: (1975)

Status report on experiment R806
por: CERN. Geneva. Intersecting Storage-Rings Committee
Publicado: (1976)

806 Foot burns in diabetic patients: A systematic review
por: Choi, Katherine J, et al.
Publicado: (2022)

Engineering and characterisation of chimeric monoclonal antibody 806 (ch806) for targeted immunotherapy of tumours expressing de2-7 EGFR or amplified EGFR
por: Panousis, C, et al.
Publicado: (2005)

Anti-GD2 mAb and Vorinostat synergize in the treatment of neuroblastoma
por: Kroesen, Michiel, et al.
Publicado: (2016)

Stability enhancement in a mAb and Fab coformulation
por: Zhang, Hongyu, et al.
Publicado: (2020)

Pan-sarbecovirus mAb protects from variants
por: Flemming, Alexandra
Publicado: (2021)

A mAb for the detection of the antiretroviral drug emtricitabine
por: Youngpairoj, Ae S., et al.
Publicado: (2022)

FISH assay development for the detection of p16/CDKN2A deletion in malignant pleural mesothelioma
por: Chung, Catherine T-S, et al.
Publicado: (2010)

Homogeneous antibody-drug conjugates: DAR 2 anti-HER2 obtained by conjugation on isolated light chain followed by mAb assembly
por: Farràs, Mercè, et al.
Publicado: (2019)

Does the Number of Bifunctional Chelators Conjugated to a mAb Affect the Biological Activity of Its Radio-Labeled Counterpart? Discussion Using the Example of mAb against CD-20 Labeled with (90)Y or (177)Lu
por: Karczmarczyk, Urszula, et al.
Publicado: (2022)

Memorandum: R806-807 correlation running
por: Willis, W J, et al.
Publicado: (1979)

R806 status report December 1978
por: CERN. Geneva. Intersecting Storage-Rings Committee
Publicado: (1978)

Novel strategy for a high-yielding mAb-producing CHO strain (overexpression of non-coding RNA enhanced proliferation and improved mAb yield)
por: Tabuchi, Hisahiro
Publicado: (2013)

Hypocalcaemia following total thyroidectomy: An analysis of 806 patients
por: Nair, C. Gopalakrishnan, et al.
Publicado: (2013)

806. Candida Gut Colonization in Critically Ill Patients
por: Adelman, Max W, et al.
Publicado: (2023)

Multiple mechanisms mediate enhanced immunity generated by mAb-inactivated F. tularensis immunogen
por: Iglesias, Bibiana V., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_kkt92n8o8usrd7mkam4r4knbqt