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Hyaluronic Acid in the Intestinal Tract: Influence of Structure, Rheology, and Mucoadhesion on the Intestinal Uptake in Rats

Oral hyaluronic acid (HA) is a ubiquitous biopolymer that has gained attention as a treatment for local or systemic diseases. Here, we prepared and characterized structures of free HA (f-HA) with a high (>10(5) Da), intermediate (≤10(5) Da), and low (≤10(4) Da) average molar mass (MM); nanopartic...

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Detalles Bibliográficos
Autores principales: Barbosa de Souza, Alexandro, Vinícius Chaud, Marco, Francine Alves, Thais, Ferreira de Souza, Juliana, Andrade Santana, Maria Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601924/
https://www.ncbi.nlm.nih.gov/pubmed/33050089
http://dx.doi.org/10.3390/biom10101422