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Identification of Differentially Methylated Regions Associated with a Knockout of SUV39H1 in Prostate Cancer Cells

Epigenetic alterations, such as histone methylations, affect the pathogenesis of tumors including prostate cancer (PCa). Previously, we reported that metformin reduced SUV39H1, a histone methyltransferase of H3 Lys9, to inhibit the migration of PCa cells. Since histone methylation is functionally li...

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Detalles Bibliográficos
Autores principales: Yan, Wenbo, Guo, Yuqi, Xu, Fangxi, Saxena, Deepak, Li, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601968/
https://www.ncbi.nlm.nih.gov/pubmed/33066102
http://dx.doi.org/10.3390/genes11101188