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Aberrant DNA Methylation of ABC Transporters in Cancer

ATP-binding cassette (ABC) transporters play a crucial role in multidrug resistance (MDR) of cancers. They function as efflux pumps, resulting in limited effectiveness or even failure of therapy. Increasing evidence suggests that ABC transporters are also involved in tumor initiation, progression, a...

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Detalles Bibliográficos
Autores principales: Zappe, Katja, Cichna-Markl, Margit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601986/
https://www.ncbi.nlm.nih.gov/pubmed/33066132
http://dx.doi.org/10.3390/cells9102281