Targeting DNA Repair, Cell Cycle, and Tumor Microenvironment in B Cell Lymphoma

The DNA double-strand break (DSB) is the most cytotoxic lesion and compromises genome stability. In an attempt to efficiently repair DSBs, cells activate ATM kinase, which orchestrates the DNA damage response (DDR) by activating cell cycle checkpoints and initiating DSB repair pathways. In physiolog...

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Detalles Bibliográficos
Autores principales: Bröckelmann, Paul J., de Jong, Mathilde R. W., Jachimowicz, Ron D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7602196/
https://www.ncbi.nlm.nih.gov/pubmed/33066395
http://dx.doi.org/10.3390/cells9102287

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7602196/
https://www.ncbi.nlm.nih.gov/pubmed/33066395
http://dx.doi.org/10.3390/cells9102287

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