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Targeting DNA Repair, Cell Cycle, and Tumor Microenvironment in B Cell Lymphoma
The DNA double-strand break (DSB) is the most cytotoxic lesion and compromises genome stability. In an attempt to efficiently repair DSBs, cells activate ATM kinase, which orchestrates the DNA damage response (DDR) by activating cell cycle checkpoints and initiating DSB repair pathways. In physiolog...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7602196/ https://www.ncbi.nlm.nih.gov/pubmed/33066395 http://dx.doi.org/10.3390/cells9102287 |