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Synthesis and Biological Evaluation of New Pyridothienopyrimidine Derivatives as Antibacterial Agents and Escherichia coli Topoisomerase II Inhibitors

The growing resistance of bacteria to many antibiotics that have been in use for several decades has generated the need to discover new antibacterial agents with structural features qualifying them to overcome the resistance mechanisms. Thus, novel pyridothienopyrimidine derivatives (2a,b–a,b) were...

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Detalles Bibliográficos
Autores principales: Mohi El-Deen, Eman M., Abd El-Meguid, Eman A., Karam, Eman A., Nossier, Eman S., Ahmed, Marwa F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7602199/
https://www.ncbi.nlm.nih.gov/pubmed/33066400
http://dx.doi.org/10.3390/antibiotics9100695