GluN2 Subunit-Dependent Redox Modulation of NMDA Receptor Activation by Homocysteine

Homocysteine (HCY) molecule combines distinct pharmacological properties as an agonist of N-methyl-d-aspartate receptors (NMDARs) and a reducing agent. Whereas NMDAR activation by HCY was elucidated, whether the redox modulation contributes to its action is unclear. Here, using patch-clamp recording...

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Detalles Bibliográficos
Autores principales: Sibarov, Dmitry A., Boikov, Sergei I., Karelina, Tatiana V., Antonov, Sergei M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7602226/
https://www.ncbi.nlm.nih.gov/pubmed/33066432
http://dx.doi.org/10.3390/biom10101441

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7602226/
https://www.ncbi.nlm.nih.gov/pubmed/33066432
http://dx.doi.org/10.3390/biom10101441

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