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Randomised prospective phase II trial in multiple brain metastases comparing outcomes between hippocampal avoidance whole brain radiotherapy with or without simultaneous integrated boost: HA-SIB-WBRT study protocol

BACKGROUND: Recent evidence supports hippocampal avoidance with whole brain radiotherapy (HA-WBRT) as the recommended treatment option in patients with good prognosis and multiple brain metastases as this results in better neurocognitive preservation compared to whole brain radiotherapy. However, th...

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Detalles Bibliográficos
Autores principales: Chia, Brendan Seng Hup, Leong, Jing Yun, Ong, Ashley Li Kuan, Lim, Cindy, Poon, Shi Hui, Chua, Melvin Lee Kiang, Chua, Kevin Lee Min, Kusumawidjaja, Grace, Chua, Eu Tiong, Wong, Fuh Yong, Lee, Tih Shih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7602352/
https://www.ncbi.nlm.nih.gov/pubmed/33126867
http://dx.doi.org/10.1186/s12885-020-07565-y