Obesity Augments Glucocorticoid-Dependent Muscle Atrophy in Male C57BL/6J Mice

Glucocorticoids promote muscle atrophy by inducing a class of proteins called atrogenes, resulting in reductions in muscle size and strength. In this work, we evaluated whether a mouse model with pre-existing diet-induced obesity had altered glucocorticoid responsiveness. We observed that all animal...

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Detalles Bibliográficos
Autores principales: Gunder, Laura C., Harvey, Innocence, Redd, JeAnna R., Davis, Carol S., AL-Tamimi, Ayat, Brooks, Susan V., Bridges, Dave
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7602414/
https://www.ncbi.nlm.nih.gov/pubmed/33076257
http://dx.doi.org/10.3390/biomedicines8100420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7602414/
https://www.ncbi.nlm.nih.gov/pubmed/33076257
http://dx.doi.org/10.3390/biomedicines8100420

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