Merkel Cell Polyomavirus Large T Antigen is Dispensable in G2 and M-Phase to Promote Proliferation of Merkel Cell Carcinoma Cells

Merkel cell carcinoma (MCC) is an aggressive skin cancer frequently caused by the Merkel cell polyomavirus (MCPyV), and proliferation of MCPyV-positive MCC tumor cells depends on the expression of a virus-encoded truncated Large T antigen (LT) oncoprotein. Here, we asked in which phases of the cell...

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Detalles Bibliográficos
Autores principales: Houben, Roland, Ebert, Marlies, Hesbacher, Sonja, Kervarrec, Thibault, Schrama, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7602435/
https://www.ncbi.nlm.nih.gov/pubmed/33066686
http://dx.doi.org/10.3390/v12101162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7602435/
https://www.ncbi.nlm.nih.gov/pubmed/33066686
http://dx.doi.org/10.3390/v12101162

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