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Non-Human Primate Blood–Brain Barrier and In Vitro Brain Endothelium: From Transcriptome to the Establishment of a New Model

The non-human primate (NHP)-brain endothelium constitutes an essential alternative to human in the prediction of molecule trafficking across the blood–brain barrier (BBB). This study presents a comparison between the NHP transcriptome of freshly isolated brain microcapillaries and in vitro-selected...

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Detalles Bibliográficos
Autores principales: Chaves, Catarina, Do, Tuan-Minh, Cegarra, Céline, Roudières, Valérie, Tolou, Sandrine, Thill, Gilbert, Rocher, Corinne, Didier, Michel, Lesuisse, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7602447/
https://www.ncbi.nlm.nih.gov/pubmed/33066641
http://dx.doi.org/10.3390/pharmaceutics12100967