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Vasoconstrictor Mechanisms in Chronic Hypoxia-Induced Pulmonary Hypertension: Role of Oxidant Signaling

Elevated resistance of pulmonary circulation after chronic hypoxia exposure leads to pulmonary hypertension. Contributing to this pathological process is enhanced pulmonary vasoconstriction through both calcium-dependent and calcium sensitization mechanisms. Reactive oxygen species (ROS), as a resul...

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Detalles Bibliográficos
Autores principales: Yan, Simin, Resta, Thomas C., Jernigan, Nikki L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7602539/
https://www.ncbi.nlm.nih.gov/pubmed/33076504
http://dx.doi.org/10.3390/antiox9100999