Metabolism-Disrupting Chemicals and the Constitutive Androstane Receptor CAR

During the last two decades, the constitutive androstane receptor (CAR; NR1I3) has emerged as a master activator of drug- and xenobiotic-metabolizing enzymes and transporters that govern the clearance of both exogenous and endogenous small molecules. Recent studies indicate that CAR participates, to...

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Detalles Bibliográficos
Autores principales: Küblbeck, Jenni, Niskanen, Jonna, Honkakoski, Paavo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7602645/
https://www.ncbi.nlm.nih.gov/pubmed/33076503
http://dx.doi.org/10.3390/cells9102306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7602645/
https://www.ncbi.nlm.nih.gov/pubmed/33076503
http://dx.doi.org/10.3390/cells9102306

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