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Genetic Alterations in the INK4a/ARF Locus: Effects on Melanoma Development and Progression

Genetic alterations in the INK4a/ARF (or CDKN2A) locus have been reported in many cancer types, including melanoma; head and neck squamous cell carcinomas; lung, breast, and pancreatic cancers. In melanoma, loss of function CDKN2A alterations have been identified in approximately 50% of primary mela...

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Detalles Bibliográficos
Autores principales: Ming, Zizhen, Lim, Su Yin, Rizos, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7602651/
https://www.ncbi.nlm.nih.gov/pubmed/33076392
http://dx.doi.org/10.3390/biom10101447