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The Mismatch Repair System (MMR) in Head and Neck Carcinogenesis and Its Role in Modulating the Response to Immunotherapy: A Critical Review

SIMPLE SUMMARY: The dysfunction of the mismatch repair system, an important mechanism for the detection and correction of DNA replication mistakes, may often lead to instability in the length of specific genetic sequences, known as microsatellites, and to the accumulation of mutations. Microsatellit...

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Detalles Bibliográficos
Autores principales: Cilona, Maria, Locatello, Luca Giovanni, Novelli, Luca, Gallo, Oreste
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7602801/
https://www.ncbi.nlm.nih.gov/pubmed/33081243
http://dx.doi.org/10.3390/cancers12103006