Predicting Antibody Neutralization Efficacy in Hypermutated Epitopes Using Monte Carlo Simulations

Human Immunodeficiency Virus 1 (HIV-1) evades adaptive immunity by means of its extremely high mutation rate, which allows the HIV envelope glycoprotein to continuously escape from the action of antibodies. However, some broadly neutralizing antibodies (bNAbs) targeting specific viral regions show t...

Descripción completa

Detalles Bibliográficos
Autores principales: Amengual-Rigo, Pep, Carrillo, Jorge, Blanco, Julià, Guallar, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7602999/
https://www.ncbi.nlm.nih.gov/pubmed/33080783
http://dx.doi.org/10.3390/polym12102392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7602999/
https://www.ncbi.nlm.nih.gov/pubmed/33080783
http://dx.doi.org/10.3390/polym12102392

Ejemplares similares